Show legend Show as text

Structure type: oligomer

• Article ID: 2824
  Saitoh K, Tsunakawa M, Konishi M, Miyaki T "Broad-spectrum aminoglycoxide antibiotic boholomycin and its manufacture with Streptomyces" - USA Patent Applications (1988) 1-9
  
   
  
  Streptomyces
  CSDB ID 149533 (all data & tools)

Show legend Show as text

Structure type: oligomer
Trivial name: boholomycin derivative
Contained glycoepitopes: IEDB_2189046

• Article ID: 2875
  Saitoh K, Tsunakawa M, Tomita K, Miyaki T, Konishi M, Kawaguchi H "Boholomycin, a new aminoglycoside antibiotic. I. Production, isolation and properties" - The Journal of Antibiotics 41 (1988) 855-861
  

  A novel aminoglycoside antibiotic, boholmycin, was produced by Streptomyces hygroscopicus H617-25 isolated from a soil sample collected in Bohol Island, the Philippines. It has a pseudotetrasaccharide structure composed of a heptose, two aminosugars and dicarbamoyl-scyllo-inositol. Intrinsic antibacterial activity of boholmycin is weak but it exhibits broad spectrum activity against Gram-positive and Gram-negative bacteria including aminoglycoside-resistant strains. Boholmycin is non-toxic in mice at 1,000 mg/kg intravenously

  NCBI PubMed ID: 3417558
  Journal NLM ID: 0151115
  Publisher: London: Nature Publishing Group
  Institutions: Bristol-Myers Research Institute, Ltd., Tokyo Research Center, Japan.
  
   
  
  Streptomyces hygroscopicus H617-25
  CSDB ID 131640 (all data & tools)