Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: leaf
NCBI PubMed ID: 10930721Publication DOI: 10.1016/s0367-326x(00)00185-4Journal NLM ID: 16930290RPublisher: Elsevier
Correspondence: adbasile
unina.it
Institutions: Dipartimento di Biologia Vegetale, Università degli Studi di Napoli 'Federico II', Naples, Italy, Istituto di Patologia Generale ed Oncologia, Facoltà di Medicina e Chirurgia, Seconda Università degli Studi, Naples, Italy, Dipartimento di Chimica Farmaceutica, Università 'Federico II', Naples, Italy
Following the extraction of Castanea sativa with an aqueous solution of sulfuric acid (pH 3.0), the ethyl acetate soluble fraction was tested for its antibacterial and allelopathic activity. The extract was shown to have pronounced antibacterial effects against seven of the eight strains of Gram-positive and Gram-negative bacteria used (MIC in the range of 64-256 μg/ml and MBC in the range of 256-512 μg/ml). The active fraction was analyzed by TLC and HPLC showing the presence of rutin, hesperidin, quercetin, apigenin, morin, naringin, galangin and kaempferol. Standards of the identified flavonoids were tested against the same bacterial strains. The highest activity was shown by quercetin, rutin and apigenin. The allelopathic effect was tested against Raphanus sativus seed germination. The extract, quercetin, rutin and apigenin caused a decrease in the percentage of seed germination and root and epicotyl growth.
antibacterial activity, flavonoids, Castanea sativa, allelopathic activity
Structure type: oligomer
C
27H
30O
16Location inside paper: abstract, p. S114, Fig. 1, rutin
Trivial name: rutin, rutoside, rutin, quercetin rutinoside, rutoside, quercetin 3-O-rutinose, quercetin-3-O-rutinoside, quercetin 3-O-rutinoside
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_144144,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192
Methods: TLC, HPLC, extraction, antibacterial assay, evaporation, germination assay
Biological activity: compound showed antibacterial activity against E. coli, K. pneumoniae, E. aerogenes, S. aureus, P. vulgaris, P. aeruginosa and E. cloacae in MIC range of 32-128 μg/ml
Related record ID(s): 64845, 64846
NCBI Taxonomy refs (TaxIDs): 21020Reference(s) to other database(s): CCSD:
50720, CBank-STR:3399
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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