Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Publication DOI: 10.1002/1099-1565(200011/12)11:6<351::AID-PCA544>3.0.CO;2-SJournal NLM ID: 9200492Publisher: Chichester, Sussex, UK: Wiley
Correspondence: Handa SS <drrljm

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Institutions: Regional Research Laboratory (C.S.I.R.), Jammu, India
A pentacyclic triterpenoid, ursolic acid (1), two iridoid glucosides, verbenalin (2) and hastatoside (3), and a phenylpropanoid glycoside, verbascoside (4), were isolated from Verbena officinalis Linn. (Verbenaceae), a plant listed in the Chinese Pharmacopoeia and the British Herbal Pharmacopoeia. A procedure for the optimised extraction of these constituents for quantitative estimations has been established. An HPTLC method was employed for the determination of 1 using Liebermann Burchard reagent. A reversed-phase HPLC system with photodiode array detector was used to resolve compounds 2, 3 and 4 in the methanol extracts of different parts of the plant. Tender parts of the plant were rich in all of these constituents (0.24–0.34%, w/w) while the roots, which are not official in the Pharmacopoeias, contained a maximum amount (0.32%, w/w) of the bioactive verbascoside (4). The assay methods described are simple, rapid and accurate, and may form part of future drug authentication protocols.
anti-inflammatory, ursolic acid, Verbenaceae, verbascoside, high pressure liquid chromatography, Verbena officinalis, verbenalin, high performance thin layer chromatography, hastatoside
Structure type: monomer
Trivial name: daucosterol, β-daucosterol, β-sitosterol, β-sitosterol-β-D-glucoside, androsine, saxifragifolin B, β-sitosterol 3-O-β-D-glucopyranoside
Compound class: saponin glycoside, glycoside, steroid glycoside, triterpene glycoside, triterpenoid glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: IR, NMR, MS, HPLC, UV, extraction, HPTLC, column chromatography, precipitation, evaporation, PTLC
Related record ID(s): 65261, 65262, 65263
NCBI Taxonomy refs (TaxIDs): 79772Reference(s) to other database(s): GenDB:MK026953.1
Show glycosyltransferases
There is only one chemically distinct structure: