Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: leaf
NCBI PubMed ID: 10784426Publication DOI: 10.1248/bpb.23.451Journal NLM ID: 9311984Publisher: Pharmaceutical Society of Japan
Institutions: Graduate School of East-West Medical Science, Kyunghee University, Seoul, South Korea, School of Pharmaceutical Science, Beijing Medical University, Beijing, China, Cheiju National University Medical School, Cheju, South Korea
Two flavonoids, quercetin-3-O-β-D-glucopyranoside (1) and quercetin-3,7-di-O-β-D-glucopyranoside (2), were isolated from the leaves of Mours alba (Moraceae). These two flavonoids exerted a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) at the concentration of 0.2 mM. Compound 2 also induced differentiation of the HL-60 cell line to express CD 66b and CD 14 antigens. These flavonoids exhibited significant free radical scavenging effects on 1, 1-diphenyl-2-picyl-hydrazyl radical.
differentiation, flavonoid, mulberry leaf
Structure type: monomer
Location inside paper: abstract
Trivial name: isoquercitrin
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, acid hydrolysis, biological assays, HPLC, UV, extraction, column chromatography, melting point determination, antioxidant activities, cell viability assay, evaporation, sonication, immunofluorescence staining
Related record ID(s): 65990
NCBI Taxonomy refs (TaxIDs): 3498Reference(s) to other database(s): CCSD:
49965, CBank-STR:953
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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