Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
NCBI PubMed ID: 10949475Publication DOI: 10.1016/s0021-9673(00)00555-0Journal NLM ID: 9318488Publisher: Amsterdam; New York: Elsevier
Correspondence: Ang CYW <cang
nctr.fda.gov>
Institutions: US Food and Drug Administration, National Center for Toxicological Research, Division of Chemistry, Jefferson, USA
A RP-HPLC method with photodiode array detection and LC–electrospray ionization (ESI) MS confirmation was established for the determination of major active components in St. John’s Wort dietary supplement capsules. The samples alternatively were extracted with ethanol–acetone (2:3) using a 55°C water-bath shaker or an ambient temperature ultrasonic bath. Extracts were separated by RP-C18 chromatography using a 95-min water–methanol–acetonitrile–trifluoroacetic acid gradient. The major components were identified by photodiode array detection and then confirmed by LC–ESI-MS. The quantification of components was performed using an internal standard (luteolin). This method may serve as a valuable tool for the quality evaluation of St. John’s Wort dietary supplement products.
food analysis, flavonoids, St. John’s Wort, Hypericum peforatum, naphthodianthrones, phloroglucinols
Structure type: monomer
Location inside paper: p. 87, Table 1
Trivial name: isoquercitrin
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: HPLC
Related record ID(s): 66577, 66578, 66579
NCBI Taxonomy refs (TaxIDs): 65561Reference(s) to other database(s): CCSD:
49965, CBank-STR:953
Show glycosyltransferases
There is only one chemically distinct structure: