Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: flower
NCBI PubMed ID: 10650074Publication DOI: 10.1021/np990271rJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Kim J <jwkim

snu.ac.kr>
Institutions: College of Pharmacy, Seoul National University, Seoul, South Korea
Three new acylated flavonol glycosides, patuletin 7-O-(6‘‘-isobutyryl)glucoside (1), patuletin 7-O-[6‘‘-(2-methylbutyryl)]glucoside (2), and patuletin 7-O-(6‘‘-isovaleryl)glucoside (3), were isolated from the n-BuOH extract of Inula britannica flowers by bioassay-guided fractionation, together with other known flavonoids. The structures were elucidated by 1D and 2D NMR, FABMS, and other spectral analyses. The eight flavonoids, including new compounds (1−3), patulitrin (7), nepitrin (8), axillarin (10), patuletin (11), and luteolin (12), showed profound antioxidant activity in DPPH assay and cytochrome-c reduction assay using HL-60 cell culture system.
Antioxidant activity, flavonol glycosides, Inula britannica, patuletin
Structure type: monomer
Location inside paper: p. 34, structure 4
Trivial name: astragalin, kaempferol 3-O-glucoside
Compound class: glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, acid hydrolysis, HPLC, alkaline hydrolysis, extraction, CI-MS, HR-ESI-MS, evaporation, centrifugation
Related record ID(s): 67308, 67309, 67310, 67312, 67313, 67314, 67315
NCBI Taxonomy refs (TaxIDs): 119176Reference(s) to other database(s): CCSD:
49928, CBank-STR:4070
Show glycosyltransferases
There is only one chemically distinct structure: