Four new phenolic glycosides, tenuifolisides A (1), B (2), C (3), and D (4) together with a known phenolic glyciside, β-D-(3-O-sinapoyl)-fructofuranosyl-α-D-(6-O-sinapoyl)-glucopyranoside (5) were isolated from the roots of Polygala tenuifolia. The structures of these new compounds were characterized as β-D-(3-O-(3,4,5-trimethoxycinnamoyl)]-fructofuranosyl-α-D-[6-O-(p-hydroxybenzoyl)]-glucopyranoside (1), β-D-(3-O-sinapoyl)-fructofuranosyl-α-D-(6-O-[p-hydroxybenzoyl)]-glucopyranoside (2), β-D-[3-O-(3,4,5-trimethoxycinnamoryl)]-fructofuranosyl-α-D-(6-O-sinapoyl)-glucopyranoside (3), and 1,5-anhydro-[6-O(3,4,5-trimethoxycinnamoryl)]-D-glucitol (4), respectively, on the basis of chemical and spectral evidence including two dimensional unclear magnetic resonance (2D-NMR) studies.
phenolic glycoside, Polygala tenuifolia, Polygalaceae, tenuifoliside A, tenuifoliside B, tenuifoliside C, tenuifoliside D
Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003628921Publisher: Pharmaceutical Society Of Japan
Institutions: Research Institute for Biology & Chemistry, Tsumura & Co., Japan
Methods: 13C NMR, 1H NMR, gel filtration, IR, FAB-MS, TLC, alkaline hydrolysis, UV
Found