Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
NCBI PubMed ID: 31414285Publication DOI: 10.1007/s00705-019-04371-1Journal NLM ID: 7506870Publisher: Wien, New York: Springer-Verlag
Correspondence: letarov
gmail.com
Institutions: N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia, S. N. Winogradsky Institute of Microbiology, Federal Research Centre, 'Fundamentals of Biotechnology', Russian Academy of Sciences, 117312, Moscow, Russian Federation, Faculty of Biology, Lomonosov Moscow State University, Moscow, Russian Federation
Several types of Escherichia coli O-antigens form highly effective shields protecting the bacterial cell surface and preventing bacteriophages from interacting directly with their secondary (terminal) receptors. However, it is not clear if O-antigens of various types (O-serotypes) differ in their anti-phage protection efficacy. Here, we describe a new E. coli strain, F5, which has an E. coli O28ab-related O-antigen. Although the amount of O-antigen produced by this strain is comparable to that produced by other E. coli strains we tested, it appears to give the cells significantly lower protection against phage attack than other O-antigen types, such as the O-polysaccharide of E. coli F17, which we studied earlier.
O-antigen, Escherichia coli, type, O-polysaccharide, bacteriophage, protection
Structure type: polymer chemical repeating unit
Location inside paper: p.2785, fig.1(b), OPS O28ab
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_130695,IEDB_135813,IEDB_137340,IEDB_141807,IEDB_142488,IEDB_146664,IEDB_151531,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, SDS-PAGE, sugar analysis, GLC, MALDI-TOF MS, HF treatment, mild acid degradation, phage assay
Related record ID(s): 735, 1017
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G73445VU
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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