An extracellular polysaccharide AVP was isolated from the fermented broth of coral-associated fungus Aspergillus versicolor LCJ-5-4. AVP was a mannoglucan with molecular weight of about 7 kDa, and the molar ratio of glucose and mannose was 1.7:1.0. On the basis of detailed one- and two-dimensional nuclear magnetic resonance (1D and NMR-2D) spectroscopic analyses, the backbone of AVP was characterized to be composed of (1→6)-linked α-d-glucopyranose and (1→2)-linked α-d-mannopyranose units. The mannopyranose residues in the backbone were substituted mainly at C-6 by the side chain of (1→2)-linked α-d-mannopyranose trisaccharides units. The antioxidant activity of AVP was evaluated with the scavenging abilities on 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide and hydroxyl radicals in vitro, and the results indicated that AVP had good antioxidant activity, especially scavenging ability on superoxide radicals. AVP was a novel extracellular polysaccharide with different structural characteristics from other extracellular polysaccharides and could be a potential source of antioxidant.

structure, extracellular polysaccharide, Antioxidant activity, Aspergillus versicolor, coral-associated fungus

• Compound ID: 18814
  

  a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-+ | -6)-a-D-Glcp-(1-6)-a-D-Glcp-(1-6)-a-D-Glcp-(1-6)-a-D-Glcp-(1-2)-a-D-Manp-(1-6)-a-D-Glcp-(1-6)-a-D-Glcp-(1-6)-a-D-Glcp-(1-

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  Structure type: structural motif or average structure ; 7000
  Compound class: EPS, O-polysaccharide, mannoglucan
  Reference(s) to other database(s): GTC:G72285EA
  
   
  
  Aspergillus versicolor LCJ-5-4
  CSDB ID 43870 (all data & tools)