Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 11454341Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: parrilli
unina.it
Institutions: Dipartimento di Chimica Organica e Biochimica, Universita di Napoli 'Federico II', via Cintia, I-80126, Naples, Italy.
A novel mild procedure for the selective cleavage of ketosidic linkages is developed using ceric ammonium nitrate (CAN) in anhydrous N,N-dimethylformamide. Its application to lipopolysaccharides (LPS) is very significant because in the so far investigated LPS, the connection between the Lipid A region and the oligo(poly)saccharide part is always a keto-sugar. This procedure has been tested on LPS of Escherichia coli which contains Kdo as a linker between Lipid A and OPS and on Acinetobacter haemoliticus which contains D-glycero-D-talo-2-octulopyranosonyl (Ko) as a linker and it performed efficiently in both cases.
O-antigen, Kdo, endotoxin, Gram-negative bacteria, ceric ammonium nitrate, D-glycero-D-talo-2-octulopyranosonic, ketosidic cleavage
Structure type: oligomer
Location inside paper: fig. 1, p.340
Aglycon: core-lipid A
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_130648,IEDB_135813,IEDB_136044,IEDB_136906,IEDB_137340,IEDB_137472,IEDB_137473,IEDB_1391962,IEDB_141794,IEDB_141807,IEDB_142078,IEDB_143794,IEDB_144990,IEDB_150899,IEDB_151528,IEDB_151531,IEDB_167071,IEDB_190606,SB_137,SB_165,SB_166,SB_187,SB_195,SB_29,SB_7,SB_88
Methods: 31P NMR, MALDI-TOF MS, selective cleavage of ketosidic linkages
NCBI Taxonomy refs (TaxIDs): 2170726
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error