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1. (Article ID: 7887)
Namikoshi M, Kobayashi H, Yoshimoto T, Meguro S, Akano K
Isolation and characterization of bioactive metabolites from marine-derived filamentous fungi collected from tropical and sub-tropical coral reefs
Chemical and Pharmaceutical Bulletin 48(10) (2000)
1452-1457
Two new compounds, paecilospirone (1) and phomopsidin (2), and seven known compounds, chaetoglobosin A (3), griseofulvin (4), fusarielin A (5), fusapyrone (6), deoxyfusapyrone (7), and verrucarins J (8) and L acetate (9), have been isolated and characterized from marine-derived fungi collected in tropical and sub-tropical coral reef environments. The utility of marine-derived fungi as a source of bioactive secondary metabolites is discussed.
isolation, Marine fungi, bioactive metabolite, paecilospirone, phomopsidin, marine natural product
NCBI PubMed ID: 11045449Publication DOI: 10.1248/cpb.48.1452Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Correspondence: namikosh
tokyo-u-fish.ac.jp
Institutions: Department of Ocean Sciences, Tokyo University of Fisheries, Tokyo, Japan, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan
Methods: 13C NMR, 1H NMR, IR, TLC, ESI-MS, biological assays, HPLC, UV, optical rotation measurement, CC, cell growth, cytotoxicity assay, evaporation, HR-FAB-MS
The publication contains the following compound(s):
- Compound ID: 19930
|
b-D-1,4dxylHexp-(1C-3)-Subst
Subst = fusapyrone aglycon = SMILES CCCCCCC(C/C(C)=C\C(/C=C(/C=C/{8}C(O)C(C)(C1=CC({3}C={2}C(O)O1)=O)C)C){27}CO)C |
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Structure type: monomer
; 607.3827 [M+H]+
C34H54O9
Trivial name: fusapyrone
Compound class: glycoside
- Compound ID: 19931
|
b-D-1,4dxylHexp-(1C-3)-Subst
Subst = deoxyfusapyrone aglycon = SMILES CCCCCCC(C/C(C)=C\C(/C=C(/C=C/{8}C(O)C(C)(C1=CC({3}C={2}C(O)O1)=O)C)C)C)C |
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Structure type: monomer
; 591.3884 [M+H]+
C34H54O8
Trivial name: deoxyfusapyrone
Compound class: glycoside
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