A novel sugar, 5,7-diacetamido-8-amino-3,5,7,8,9-pentadeoxy-D: -glycero-D: -galacto-non-2-ulosonic acid (NonlA), has been identified as a component of the oligosaccharide (OS) isolated from the lipooligosaccharide (LOS) of the emerging strain of Vibrio parahaemolyticus O3:K6 associated with a global pandemic. In the present study we report the identification and characterization of this novel sugar present in the OS of V. parahaemolyticus O3:K6, using chemical analysis, NMR spectroscopy and mass spectrometry
oligosaccharide, Lipooligosaccharide, 5, 7, Vibrio parahaemolyticus O3:K6, NonlA, 7-diacetamido-8-amino-3, 8, 9-pentadeoxy-D-glycero-D-galacto-non-2-ulosonic acid
NCBI PubMed ID: 17994291Journal NLM ID: 8603310Publisher: Kluwer Academic Publishers
Correspondence: aksen@iicb.res.in
Institutions: Department of Chemistry (Carbohydrate), Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata, 700032, India
Methods: 13C NMR, 1H NMR, methylation, GLC-MS, NMR-2D, HF solvolysis, sugar analysis, ESI-MS, GLC, mild acid hydrolysis, MALDI-TOF MS, NMR-1D, methanolysis
Found