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1. (Article ID: 8429)
 
Maity P, Sen IK, Maji PK, Paloi S, Devi KS, Acharya K, Maiti TK, Islam SS
Structural, immunological, and antioxidant studies of β-glucan from edible mushroom Entoloma lividoalbum
Carbohydrate Polymers 123 (2015) 350-358
 

A water soluble β-glucan having molecular weight 200000 Da was isolated from hot water extract of the fruit bodies of an edible mushroom Entoloma lividoalbum (Kühner & Romagn) Kubička. This polysaccharide (ELPS) contains (1→3,6)-β-D-Glcp, (1→3)-β-D-Glcp, (1→6)-β-D-Glcp, and terminal β-D-Glcp moieties in a molar ratio of nearly 1:1:3:1. Chemical and spectroscopic analysis showed that the backbone of glucan consists of three (1→6)-β-D-glucopyranosyl and two (1→3)-β-D-glucopyranosyl residues, out of which one (1→3)-β-D-glucopyranosyl moiety was branched at O-6 with a terminal β-D-glucopyranosyl residue. This β-glucan exhibited macrophage, splenocyte, and thymocyte stimulations. It possesses promising antioxidant activities as evidenced from its hydroxyl and superoxide radical scavenging activities and reducing properties

immunostimulation, β-D-glucan, NMR studies, antioxidant properties, Entoloma lividoalbum

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