A water-soluble polysaccharide called PC-2 was previously isolated from Flavoparmelia caperata (L.) Hale and assigned to α(1-3)(1-4)glucan. However, PC-2 separated into three components, PC-2A, PC-2B, and PC-2C (a single peak in HPLC, respectively) on further purification. Methylation analysis and 1H- and 13C-NMR spectroscopic studies suggested that PC-2A is composed of repeating units of [α-D-Glc1-3](3), : [α-D-Glc1-4](2), while PC-2B and PC-2C are partly branched galactoglucomannans consisting of (1-3)- and (1-4)-linked α-D-glucopyranosyl units as the main chain. In addition we confirmed that the polysaccharide fraction PB-2 from the lichen of the same genus, Flavoparmelia baltimorensis (Gyelink & Foriss) Hale, is identical to PC-2 based on the chemical and spectroscopic data
NCBI PubMed ID: 14646326Publication DOI: 10.1248/cpb.51.1436Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Correspondence: Takeda-td
kyoritsu-ph.ac.jp
Institutions: Kyoritsu College of Pharmacy, Tokyo, Japan, Meiji Pharmaceutical University, Kiyose, Japan, College of Pharmacy, Nihon University, Funabashi, Japan, Shibata Laboratory of Natural Medicinal Materials, Tokyo, Japan
Methods: 13C NMR, 1H NMR, methylation, NMR-2D, GC-MS, acid hydrolysis, GC, extraction, optical rotation measurement, acetylation, reduction, CC, precipitation
Found