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1. (Article ID: 8704)
 
Oleinikova GK, Denisenko VA, Berdyshev DV, Pushilin MA, Kirichuk NN, Menzorova NI, Kuzmich AS, Yurchenko EA, Zhuravleva OI, Afiyatullov SS
Two new sesterterpenoids, terretonins H and I, from the marine-derived fungus Aspergillus ustus
Phytochemistry Letters 17 (2016) 135-139
 

Two new sesterterpenoids, terretonins H(1) and I(2), together with two known compounds, strobilactone A(3) and cerebroside D(4), were isolated from the lipophilic extract of the marine-derived fungus Aspergillus ustus KMM 4664. The structures of compounds 1 and 2 were determined based on spectroscopic methods and confirmed by X-ray crystallographic analysis of terretonin H. All compounds were tested for cytotoxic and embryotoxic effects using sperm and developing embryos of the sea urchin Strongylocentrotus intermedius and human cancer cells.

terretonin, sesterterpenoids, Aspergillus ustus, Strongylocentrotus intermedius

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