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1. (Article ID: 905)
Kosma P, Reiter A, Zamyatina A, Wimmer N, Glück A, Brade H
Synthesis of inner core antigens related to Chlamydia, Pseudomonas and Acinetobacter LPS
Journal of Endotoxin Research 5(3) (1999)
157-163
synthesis, antigen, core, Pseudomonas, Acinetobacter, antigens, Chlamydia, inner core
Journal NLM ID: 9433350Publisher: Maney Publishing
Institutions: Institute of Chemistry, University of Agricultural Sciences, Vienna, Wien, Austria
The publication contains the following compound(s):
- Compound ID: 2653
Structure type: oligomer
Trivial name: cross-reactive epitope
Compound class: core oligosaccharide, LPS
Reference(s) to other database(s): GlycomeDB:
5771
- Compound ID: 2651
Structure type: oligomer
Reference(s) to other database(s): GlycomeDB:
11207
- Compound ID: 2652
Structure type: oligomer
Reference(s) to other database(s): GlycomeDB:
25838
- Compound ID: 2654
Structure type: oligomer
Reference(s) to other database(s): GlycomeDB:
15477
- Compound ID: 818
Structure type: oligomer
Reference(s) to other database(s): GlycomeDB:
25793
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2. (Article ID: 4790)
Pokorny B, Kosma P
First and stereoselective synthesis of an α-(2→5)-linked disaccharide of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)
Organic Letters 17(1) (2015)
110-113
Resistance of bacterial pathogens toward antibiotics has revived interest in lipopolysaccharide (LPS) motifs as potential therapeutic targets. The LPS of several pathogenic Acinetobacter strains comprises a 4,5-branched Kdo trisaccharide containing an uncommon (2→5)-linkage. In this contribution the first stereoselective glycosylation method for obtaining an α-Kdo-(2→5)-α-Kdo disaccharide in good yield is highlighted. The synthetic approach used for accessing this linkage type will allow for future studies of the immunoreactivity associated with this unique bacterial Kdo inner core structure.
Lipopolysaccharide, 3-deoxy-D-manno-oct-2-ulosonic acid, Acinetobacter, Kdo, inner core, glycosylation, immunoreactivity
NCBI PubMed ID: 25496419Publication DOI: 10.1021/ol5033128Journal NLM ID: 100890393Publisher: American Chemical Society
Correspondence: paul.kosma
boku.ac.at
Institutions: Department of Chemistry, University of Natural Resources and Life Sciences-Vienna, Muthgasse 18, A-1190 Vienna, Austria
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, chemical synthesis, chemical methods, NMR-1D, glycosylation
The publication contains the following compound(s):
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