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Structure type: polymer chemical repeating unit
Compound class: O-antigen

• Article ID: 4113
  Silipo A, Leone MR, Erbs G, Lanzetta R, Parrilli M, Chang WS, Newman MA, Molinaro A "A Unique Bicyclic Monosaccharide from the Bradyrhizobium Lipopolysaccharide and Its Role in the Molecular Interaction with Plants" - Angewandte Chemie, International Edition 50(52) (2011) 12610-12612
  

  Sugar coat: The nitrogen-fixing soil bacterium Bradyrhizobium sp. BTAi1 is coated with a unique lipopolysaccharide that does not induce innate immune responses in its host plant Aeschynomene indica or in different plant families. The chemical nature of the monosaccharide forming the polymer (see picture) is unprecedented in nature, which helps to avoid 'harmful' recognition by its symbiotic host.

  Lipopolysaccharide, Bradyrhizobium, bradyrhizose, microbe–plant interaction, O-antige

  NCBI PubMed ID: 22058060
  Publication DOI: 10.1002/anie.201106548
  Journal NLM ID: 0370543
  Publisher: Weinheim: Wiley-VCH
  Correspondence: molinaro@unina.it
  Institutions: Department of Organic Chemistry and Biochemistry, University of Naples 'Federico II', Via Cinthia 4, 80126 Napoli (Italy)
  Methods: 13C NMR, 1H NMR, NMR-2D, SDS-PAGE, sugar analysis, chemical analysis, MALDI-TOF MS, MD simulations, CD, molecular mechanics
  
   
  
  Bradyrhizobium sp. BTAi1
  CSDB ID 26349 (all data & tools)

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Structure type: oligomer
Compound class: O-antigen

• Article ID: 5806
  Li R, Yu H, Chen X "Recent progress in chemical synthesis of bacterial surface glycans" - Current Opinion in Chemical Biology 58 (2020) 121-136
  

  With the continuing advancement of carbohydrate chemical synthesis, bacterial glycomes have become increasingly attractive and accessible synthetic targets. Although bacteria also produce carbohydrate-containing secondary metabolites, our review here will cover recent chemical synthetic efforts on bacterial surface glycans. The obtained compounds are excellent candidates for the development of improved structurally defined glycoconjugate vaccines to combat bacterial infections. They are also important probes for investigating glycan–protein interactions. Glycosylation strategies applied for the formation of some challenging glycosidic bonds of various uncommon sugars in a number of recently synthesized bacterial surface glycans are highlighted.

  synthesis, carbohydrate, glycosyltransferase, glycoconjugate vaccine, Bacterial glycan

  NCBI PubMed ID: 32920523
  Publication DOI: 10.1016/j.cbpa.2020.08.003
  Journal NLM ID: 9811312
  Publisher: London: Elsevier
  Correspondence: Chen Xi
  Institutions: Department of Chemistry, University of California Davis, Davis, CA, USA
  
   
  
  Bradyrhizobium sp. BTAi1
  CSDB ID 5119 (all data & tools)