Found 75 structures.
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Next 15 structure(s)
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1. Compound ID: 5518
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-6)-Manp-(1-3)-Glcp-(1-6)-Manp-(1-3)-Glcp-(1-3)-b-GlcpA-(1-3)-a-Galp-(1- |
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Structure type: polymer chemical repeating unit
Compound class: K-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_136906,IEDB_137472,IEDB_137485,IEDB_1394182,IEDB_140630,IEDB_141794,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_152206,IEDB_190606,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_67,SB_7,SB_72
The structure is contained in the following publication(s):
- Article ID: 2342
Nhan LB, Jann B, Jann K "Immunochemistry of K antigens of Escherichia coli. The K29 antigen of E. coli O9:K29(A):H-" -
European Journal of Biochemistry 21 (1971) 226-234
Journal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
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2. Compound ID: 7759
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a-D-Glcp-(1-6)-+
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b-D-GlcpA-(1-6)-+ |
| |
-3)-a-D-Manp-(1-3)-a-D-Manp-(1-3)-a-D-Glcp-(1- |
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Structure type: polymer chemical repeating unit
Compound class: EPS
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
- Article ID: 5791
Knirel YA, Van Calsteren M "Bacterial exopolysaccharides" -
Book: Comprehensive Glycoscience: From Chemistry to Systems Biology. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering (2021) 1-75
Bacterial extracellular polysaccharides are known as a cell-bound capsule, a sheath, or a slime, which is excreted into the environment. They play an important role in virulence of medical bacteria and plant-to-symbiont interaction and are used for serotyping of bacteria and production of vaccines. Some exopolysaccharides have commercial applications in industry, and claims of health benefits have been documented for an increasing number of them. Exopolysaccharides have diverse composition and structure, and some contain sugar and non-sugar components that are found in bacterial carbohydrates only. The present article provides an updated collection of the data on exopolysaccharides of various classes of gram-negative and gram-positive bacteria reported until the end of 2019. When known, biosynthesis pathways of exopolysaccharides are treated in a summary manner. References are made to structure and biosynthesis relatedness between exopolysaccharides of different bacterial taxa as well as between bacterial polysaccharides and mammalian glycosaminoglycans.
polysaccharide structure, Gram-negative bacteria, capsule, Biofilm, polysaccharide biosynthesis, gram-positive bacteria, Monosaccharide composition, Bacterial exopolysaccharide, non-sugar component
Publication DOI: 10.1016/B978-0-12-819475-1.00005-5Publisher: Elsevier
Correspondence: marie-rose.vancalsteren@canada.ca; yknirel@gmail.com
Editors: Barchi J, Kamerling H
Institutions: N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia, Saint-Hyacinthe Research and Development Centre, Agriculture and Agri-Food Canada, Saint-Hyacinthe, QC, Canada
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3. Compound ID: 7760
Structure type: oligomer
Contained glycoepitopes: IEDB_130701,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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4. Compound ID: 7761
Structure type: oligomer
Contained glycoepitopes: IEDB_137485,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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5. Compound ID: 7768
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a-D-Glcp-(1-6)-+
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-a-D-Manp-(1-3)-a-D-Glc |
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Structure type: oligomer
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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6. Compound ID: 7769
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a-D-Glcp-(1-6)-+
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-a-D-Manp-(1-3)-b-D-Glc |
Show graphically |
Structure type: oligomer
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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7. Compound ID: 7770
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a-D-Glcp-(1-6)-+
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a-D-Glcp-(1-3)-+ |
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-a-D-Man |
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Structure type: oligomer
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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8. Compound ID: 7771
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a-D-Glcp-(1-6)-+
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a-D-Glcp-(1-3)-+ |
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-b-D-Man |
Show graphically |
Structure type: oligomer
Contained glycoepitopes: IEDB_115136,IEDB_130701,IEDB_137485,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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9. Compound ID: 7773
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a-D-Glcp-(1-6)-+
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-a-D-Manp-(1-3)-D-Glc-ol |
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Structure type: oligomer
Trivial name: pentasaccharide-alditol
Contained glycoepitopes: IEDB_114708,IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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10. Compound ID: 7774
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a-D-Glcp-(1-6)-+
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a-D-Glcp-(1-3)-+ |
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b-D-GlcpA-(1-6)-a-D-Manp-(1-3)-a-D-Manp-(1-3)-D-Glc-ol |
Show graphically |
Structure type: oligomer
Trivial name: pentasaccharide-alditol
Contained glycoepitopes: IEDB_114708,IEDB_115136,IEDB_130701,IEDB_140630,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_164174,IEDB_423153,IEDB_983930,IEDB_983931,SB_192,SB_197,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3461
Dobruchowska JM, Gerwig GJ, Babuchowski A, Kamerling JP "Structural studies on exopolysaccharides produced by three different propionibacteria strains" -
Carbohydrate Research 343(4) (2008) 726-745
The exopolysaccharides produced by three propionibacteria strains, Propionibacterium freudenreichii 109, Propionibacterium freudenreichii 111, and Propionibacterium thoenii 126, grown on whey-based media, were found to be charged heteropolymers, composed of d-glucose, d-mannose, and d-glucuronic acid in molar ratios of 2:2:1. By means of methylation analysis, mass spectrometry, partial acid hydrolysis, and 1D/2D NMR ((1)H and (13)C) studies, it was determined that all three exopolysaccharides contain the same branched, pentasaccharide repeating unit:
NMR, structural analysis, exopolysaccharide, EPS, MS, Propionibacterium
NCBI PubMed ID: 18184608Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: j.p.kamerling@uu.nl
Institutions: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Utrecht, The Netherlands, Chair of Food Biotechnology, University of Warmia and Mazury, Heweliusza 1, 10-957 Olsztyn, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GLC-EI-MS, partial acid hydrolysis, sugar analysis, GLC, MALDI-TOF MS
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11. Compound ID: 8318
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GalpA6NH2-(1--P--?)--+
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Manp-(1-?)-Manp-(1-?)-Glcp-(1-?)-Manp-(1-?)-Kdop-(2--/lipid A/ |
Show graphically |
Structure type: oligomer
Aglycon: lipid A
Trivial name: core region
Compound class: core oligosaccharide
Contained glycoepitopes: IEDB_130650,IEDB_130701,IEDB_133966,IEDB_136104,IEDB_137485,IEDB_1394182,IEDB_141793,IEDB_141836,IEDB_142488,IEDB_143632,IEDB_144983,IEDB_144995,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_153219,IEDB_153220,IEDB_164174,IEDB_164479,IEDB_474450,IEDB_983930,IEDB_983931,SB_136,SB_192,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3622
Knirel YA, Kochetkov NK "The structure of lipopolysaccharides of gram-negative bacteria. II. The structure of the core region" -
Biochemistry (Moscow) 58(2) (1993) 84-99
This review summarizes data on the structure of the core of bacterial lipopolysaccharides (LPS), an oligosaccharide which binds the lipid moiety of LPS to the O-antigenic polysaccharide chain. Both S-strains with complete LPS and R-mutants having various defects of core biosynthesis are considered. The role of the core in the functioning of the outer membrane and in the manifestation of antigenic specificity of LPS is discussed.
Lipopolysaccharide, antigen, lipopolysaccharides, LPS, structure, core, bacteria, core region, region, Gram-negative bacteria, gram negative bacteria, Gram-negative, review, outer membrane, bacterial lipopolysaccharide
Journal NLM ID: 0376536Publisher: Nauka/Interperiodica
Institutions: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow (Russian Federation)
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12. Compound ID: 10267
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/Variants 0/-+
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D-Glc-(1-?)-D-Man-(1-1)-Gro
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/Variants 1/-+
/Variants 0/ is:
aiMar-(1-3)-
OR (exclusively)
aiMar-(1-3)-
/Variants 1/ is:
aiMar-(1-2)-
OR (exclusively)
aiC15-(1-2)- |
Show graphically |
Structure type: oligomer
Contained glycoepitopes: IEDB_130701,IEDB_137485,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_153219,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 4254
Lang S "Biological amphiphiles (microbial biosurfactants)" -
Current Opinion in Colloid and Interface Science 7(1-2) (2002) 12-20
Low- and high-molecular-weight biosurfactants are of great interest because of their physicochemical and biological properties, which can be exploited in oil, food, cosmetic and pharmaceutical industries. As for the general types of microbial amphiphiles, the data accumulated over recent years are adding new interesting molecular structures to well-known compounds. Using new strains and cultivation conditions, positive results were found in basic studies of lowering the surface tension of water (72 mN/m ? 27 mN/m, cmc: 150 mg/l; rhamnose lipids from Pseudomonas aeruginosa), of size determinations of micelles and vesicles (iturin A, a lipopeptide from Bacillus subtilis), of emulsifying properties, biological activities, as well as of application tests in soil remediation.
biosynthesis, review, rhamnose, glycolipid, preparation, lipids, surfactant, surface properties, physicochemical properties, surface tension, emulsifying power, microorganism, lipopeptide, biological properties
Publication DOI: 10.1016/S1359-0294(02)00007-9Journal NLM ID: 9614964Publisher: Current Science
Correspondence: s.lang@tu-bs.de
Institutions: Technical University of Braunschweig, Institute of Biochemistry and Biotechnology, Biotechnology Group, Spielmannstr. 7, D-38106 Braunschweig, Germany, Technical University of Braunschweig, Institute of Biochemistry and Biotechnology, Biotechnology Group, Spielmannstr. 7, 38106 Braunschweig, ALLEMAGNE
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13. Compound ID: 10623
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a-D-Glcp-(1-6)-+
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b-D-GlcpN-(1-6)-+ |
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b-D-GlcpN-(1-6)-b-D-GlcpN-(1-4)-b-D-GlcpN-(1-3)-a-D-Manp-(1-5)-2,7anhKdo |
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Structure type: oligomer
Compound class: core oligosaccharide
Contained glycoepitopes: IEDB_130701,IEDB_137340,IEDB_141807,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_152206,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 4340
Kubler-Kielb J, Vinogradov E "The study of the core part and non-repeating elements of the O-antigen of Brucella lipopolysaccharide" -
Carbohydrate Research 366 (2013) 33-37
Brucella is an animal and human pathogen that expresses several virulence factors required for host cell invasion and intracellular survival. It produces LPS with unusually low toxicity, which hampers the detection of bacteria by the host immune system and thus provides resistance against intracellular antimicrobial mechanisms of the host. By chemical and spectroscopic methods we determined the structure of the LPS core and of a non-repetitive oligosaccharide fragment at the reducing end of the O-specific polysaccharide. These data should be useful for understanding the biological role of the Brucella LPS.
NMR, LPS, structure, Brucella, MS
NCBI PubMed ID: 23261780Publication DOI: 10.1016/j.carres.2012.11.004Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: E. Vinogradov
Institutions: Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA, National Research Council, Ottawa, ON, Canada K1A 0RA6
Methods: 13C NMR, 1H NMR, methylation, GC-MS, NMR, sugar analysis, mild acid hydrolysis, periodate oxidation, CE-MS, reduction with NaBD4, MR-2D
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14. Compound ID: 10624
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a-D-Glcp-(1-6)-+
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b-D-GlcpN-(1-6)-+ |
| |
b-D-GlcpN-(1-4)-b-D-GlcpN-(1-3)-a-D-Manp-(1-5)-2,7anhKdo |
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Structure type: oligomer
Compound class: core oligosaccharide
Contained glycoepitopes: IEDB_130701,IEDB_137340,IEDB_141807,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_152206,IEDB_983930,IEDB_983931,SB_192,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 4340
Kubler-Kielb J, Vinogradov E "The study of the core part and non-repeating elements of the O-antigen of Brucella lipopolysaccharide" -
Carbohydrate Research 366 (2013) 33-37
Brucella is an animal and human pathogen that expresses several virulence factors required for host cell invasion and intracellular survival. It produces LPS with unusually low toxicity, which hampers the detection of bacteria by the host immune system and thus provides resistance against intracellular antimicrobial mechanisms of the host. By chemical and spectroscopic methods we determined the structure of the LPS core and of a non-repetitive oligosaccharide fragment at the reducing end of the O-specific polysaccharide. These data should be useful for understanding the biological role of the Brucella LPS.
NMR, LPS, structure, Brucella, MS
NCBI PubMed ID: 23261780Publication DOI: 10.1016/j.carres.2012.11.004Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: E. Vinogradov
Institutions: Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA, National Research Council, Ottawa, ON, Canada K1A 0RA6
Methods: 13C NMR, 1H NMR, methylation, GC-MS, NMR, sugar analysis, mild acid hydrolysis, periodate oxidation, CE-MS, reduction with NaBD4, MR-2D
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15. Compound ID: 12209
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a-D-Glcp-(1-3)-a-D-Glcp-(1-6)-a-D-Glcp-(1-6)-+ b-D-Galp-(1-2)-b-D-Glcp-(1-6)-+
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-4)-a-D-Manp-(1-6)-a-D-Manp-(1-4)-b-D-Glcp-(1-3)-b-D-Glcp-(1-4)-a-D-Galp-(1- |
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Structure type: polymer chemical repeating unit
; n=122
Compound class: EPS
Contained glycoepitopes: IEDB_130701,IEDB_136044,IEDB_136906,IEDB_137472,IEDB_141793,IEDB_141794,IEDB_141806,IEDB_141836,IEDB_142488,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_152206,IEDB_153220,IEDB_153543,IEDB_190606,IEDB_241101,IEDB_983930,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_198,SB_44,SB_67,SB_7,SB_72,SB_88
The structure is contained in the following publication(s):
- Article ID: 4854
Li W, Tang W, Ji J, Xia X, Rui X, Chen X, Jiang M, Zhou J, Dong M "Characterization of a novel polysaccharide with anti-colon cancer activity from Lactobacillus helveticus MB2-1" -
Carbohydrate Research 411 (2015) 6-14
The present study aimed at investigating the potential anti-colon cancer activity of three purified exopolysaccharides fractions (LHEPS-1, LHEPS-2 and LHEPS-3) from the Lactobacillus helveticus MB2-1. The experimental evidence showed that LHEPS-1 significantly inhibited cell proliferation of human colon cancer Caco-2 cells in both time- and concentration-dependent manners. In contrast, no significant improvements of the inhibitory effects of LHEPS-2 and LHEPS-3 on Caco-2 cells were observed with increasing sample concentrations or prolonged incubation time. Furthermore, the structure of LHEPS-1 was elucidated using methylated analysis, gas chromatography-mass spectroscopy (GC-MS) and nuclear magnetic resonance spectroscopy (NMR), including one- and two-dimensional nuclear magnetic resonance (1D and 2D NMR). Results indicated that the LHEPS-1 consisted of a decasaccharide repeating unit with the following structure (n approximately 122) Our results suggested that the LHEPS-1 produced by L. helveticus MB2-1 might be suitable for using as natural anti-colon cancer drugs and functional foods ingredients.
nuclear magnetic resonance spectroscopy, Structural characterization, Anti-colon cancer activity, Lactobacillus helveticus MB2-1, methylated analysis
NCBI PubMed ID: 25942063Publication DOI: 10.1016/j.carres.2014.12.014Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: dongms@njau.edu.cn
Institutions: Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu 210095, PR China, College of Food Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu 210095, PR China
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GC-MS, sugar analysis, acid hydrolysis, biological assays, NMR-1D, statistical analysis
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Next 15 structure(s)
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