Found 187 structures.
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1. Compound ID: 8901
/Variants 0/-+
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{{{-a-D-Manp-(1-6)-}}}a-D-Manp
/Variants 0/ is:
{{{-a-D-Manp-(1-2)-}}}/n=0-?/-a-D-Manp-(1-2)-
OR (exclusively)
{{{-b-D-Manp-(1-2)-}}}Sug-(1-2)-
Sug = unassigned monosaccharide |
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Structure type: structural motif or average structure
Trivial name: cell-surface mannan
Contained glycoepitopes: IEDB_130701,IEDB_131173,IEDB_133966,IEDB_133967,IEDB_134618,IEDB_136104,IEDB_137485,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_144995,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_1539315,IEDB_164480,IEDB_173895,IEDB_76920,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_858578,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 3844
Ferreira JA, Azevedo NF, Vieira MJ, Figueiredo C, Goodfellow BJ, Monteiro MA, Coimbra MA "Identification of cell-surface mannans in a virulent Helicobacter pylori strain" -
Carbohydrate Research 345(6) (2010) 830-838
With the intent of contributing to a carbohydrate-based vaccine against the gastroduodenal pathogen, Helicobacter pylori, we report here the structure of cell-surface mannans obtained from a virulent strain. Unlike other wild-type strains, this strain was found to express in good quantities this polysaccharide in vitro. Structural analysis revealed a branched mannan formed by a backbone of α-(1→6)-linked mannopyranosyl residues with approximately 80% branching at the O-2 position. The branches were composed of O-2-linked Man residues in both α- and β-configurations: [abstract: see text]. In addition, this strain also expressed cell-surface emblematic H. pylori lipopolysaccharides (LPS) containing partially fucosylated polyLacNAc O-chains. Affinity assays with polymyxin-B and concanavalin A revealed no association between the mannan and the LPS. The described mannans may be implicated in the mediation of host-microbial interactions and immunological modulation.
Lipopolysaccharide, Helicobacter pylori, vaccine, mannan, cell-surface glycans
NCBI PubMed ID: 20227685Publication DOI: 10.1016/j.carres.2010.01.022Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: mac@ua.pt
Institutions: Departamento de Química, Universidade de Aveiro, Aveiro, Portugal, LEPAE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Porto, Portugal, Centro de Engenharia Biológica, Universidade do Minho, Campus de Gualtar, Braga, Portugal, Institute of Molecular Pathology and Immunology, University of Porto, Portugal, Medical Faculty of Porto, Porto, Portugal, CICECO, University of Aveiro, Aveiro, Portugal, Department of Chemistry, University of Guelph, Guelph, ON, Canada
Methods: 13C NMR, 1H NMR, NMR-2D, 31P NMR, composition analysis, affinity chromatography
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2. Compound ID: 14529
SUG-(1-6)-b-D-Glcp-(1-6)-+
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-6)-+ | |
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-2)-{{{-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-2)-}}}a-D-Manp-(1-6)-a-D-Manp-(1-2)-a-D-Manp-(1- |
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Structure type: structural motif or average structure
; 51330
Compound class: EPS
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_142488,IEDB_143632,IEDB_144983,IEDB_146664,IEDB_152206,IEDB_153220,IEDB_164480,IEDB_76933,IEDB_983930,IEDB_983931,SB_136,SB_191,SB_192,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 5768
Gan L, Li X, Zhang H, Zhang R, Wang H, Xu Z, Peng B, Tian Y "Preparation, characterization and functional properties of a novel exopolysaccharide produced by the halophilic strain Halomonas saliphila LCB169T" -
International Journal of Biological Macromolecules 156 (2020) 372-380
A novel exopolysaccharide, designated hsEPS, was successfully prepared from the high-salt-fermented broth of a novel species Halomonas saliphila LCB169T by ethanol precipitation, anion-exchange and gel-filtration chromatography, and its structure was well-characterized by means of chemical and spectral analyses. Results showed that hsEPS was primarily composed of mannose and glucose with a relative weight-average molecular weight of 5.133 × 104 g/mol. It was deduced that the major backbone contained (1→2)-linked α-D-Manp and (1→6)-linked α-D-Manp with branches substituted at C-2 by T-α-D-Manp and at C-6 by the fragment of T-α-D-Manp-(1→2)-α-D-Manp-(1→. A sheet-like structure was observed under high magnification. The water solubility index, water holding capacity, oil holding capacity and foaming capacity of hsEPS were 98.0, 19.3, 1386.7 and 82.2%, respectively. It also exhibited outstanding emulsifying activity against all tested edible oils. Together, the resulted data indicated that hsEPS might serve as an active ingredient in food, cosmetics and detergents.
structure, exopolysaccharide, halophiles, Functional properties, Halomonas saliphila
NCBI PubMed ID: 32289411Publication DOI: 10.1016/j.ijbiomac.2020.04.062Journal NLM ID: 7909578Publisher: Butterworth-Heinemann
Correspondence: pengbiyu@scu.edu.cn; yqtian@scu.edu.cn
Institutions: College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, PR China, Key Laboratory of Leather Chemistry and Engineering (Sichuan University), Ministry of Education, Chengdu 610065, PR China
Methods: gel filtration, 13C NMR, 1H NMR, NMR-2D, methylation, GC-MS, sugar analysis, FTIR, HPAEC-PAD, SEM, HPSEC-RI-MALLS, WSI, WHC, OHC
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3. Compound ID: 15937
a-D-Manp-(1-6)-+
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a-D-Manp-(1-6)-+ |
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-6)-a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-?)-a-D-Manp-(1- |
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Structure type: structural motif or average structure
; 10026
Trivial name: G-EPS
Compound class: EPS
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72,SB_77
The structure is contained in the following publication(s):
- Article ID: 6175
Zhai Z, Chen A, Zhou H, Zhang D, Du X, Liu Q, Wu X, Cheng J, Chen L, Hu F, Liu Y, Su P "Structural characterization and functional activity of an exopolysaccharide secreted by Rhodopseudomonas palustris GJ-22" -
International Journal of Biological Macromolecules 167(15) (2021) 160-168
One water exopolysaccharide, designated G-EPS, was secreted by Rhodopseudomonas palustris GJ-22 culture media. The structure of G-EPS was characterized with HPGPC, GC–MS, methylation, 1D and 2D NMR, along with UV and FT-IR spectrum. The G-EPS molecular weight was 10.026 kilodalton, and is composed of D-mannose (92.8%) and d-glucose (7.2%). The purified G-EPS promoted plant growth and induced systemic resistance against TMV in Nicotiana benthamiana. These results suggested that G-EPS is an important active component of the bio-control capacity of GJ-22.
characterization, exopolysaccharide, Rhodopseudomonas palustris, Induce systemic resistance (ISR)
Publication DOI: 10.1016/j.ijbiomac.2020.11.165Journal NLM ID: 7909578Publisher: Butterworth-Heinemann
Correspondence: Yong Liu
; Pin Su
Institutions: Longping Branch, Graduate School of Hunan University, Changsha 410125, China, Hunan Plant Protection Institute, Hunan Academy of Agricultural Sciences, Changsha 410125, China, Agricultural and Rural Bureau of Changsha County, Changsha, China, Ecological Environment Testing Center of Changsha, Changsha 410001, China
Methods: 13C NMR, 1H NMR, NMR-2D, methylation, GC-MS, ESI-MS, acid hydrolysis, GLC, FTIR, composition analysis, HPLC, UV, RT-PCR, statistical analysis, HPGPC, plant growth promotion, TMV infection
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4. Compound ID: 16236
a-D-Manp-(1-6)-+ a-D-Manp-(1-6)-+ a-D-Manp-(1-6)-+
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-2)-a-D-Manp-(1-6)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1- |
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Structure type: polymer chemical repeating unit
Compound class: EPS
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_164480,IEDB_76933,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6297
Qi M, Zheng C, Wu W, Yu G, Wang P "Exopolysaccharides from Marine Microbes: Source, Structure and Application" -
Marine Drugs 20(8) (2022) 512
The unique living environment of marine microorganisms endows them with the potential to produce novel chemical compounds with various biological activities. Among them, the exopolysaccharides produced by marine microbes are an important factor for them to survive in these extreme environments. Up to now, exopolysaccharides from marine microbes, especially from extremophiles, have attracted more and more attention due to their structural complexity, biodegradability, biological activities, and biocompatibility. With the development of culture and separation methods, an increasing number of novel exopolysaccharides are being found and investigated. Here, the source, structure and biological activities of exopolysaccharides, as well as their potential applications in environmental restoration fields of the last decade are summarized, indicating the commercial potential of these versatile EPS in different areas, such as food, cosmetic, and biomedical industries, and also in environmental remediation.
structure, exopolysaccharides, EPS, marine microorganisms, biological activities, environmentalremediation
NCBI PubMed ID: 36005515Publication DOI: 10.3390/md20080512Journal NLM ID: 101213729Publisher: Basel, Switzerland: Molecular Diversity Preservation International
Correspondence: W. Wu
; G. Yu ; P. Wang
Institutions: College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China, Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China, Key Laboratory of Marine Drugs, Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China
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5. Compound ID: 16418
a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Manp-(1-3)-+ |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp |
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Structure type: oligomer
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6379
Kogan G, Pavliak V, Masler L "Structural studies of mannans from the cell walls of the pathogenic yeasts Candida albicans serotypes A and B and Candida parapsilosis" -
Carbohydrate Research 172 (1988) 243-253
A comparative study of three cell-wall mannans, of Candida albicans serotypes A and B and Candida parapsilosis, by means of methylation analysis supports a model of yeast mannans as having an α-(1----6)-linked backbone with some units (depending on the origin of the mannan) being substituted at O-2 with oligosaccharides joined by α-(1---2) and, to a lesser extent, by α-(1----3) glycosidic bonds. Branching points in the side chains of Candida albicans mannans were found in substantial proportions for the first time, and the corresponding branched hexasaccharides were isolated by means of acetolysis and subsequent gel filtration. 13C-N.m.r. spectroscopy of the mannans, as well as a 1H-n.m.r. spectroscopic study of the oligosaccharides obtained on acetolysis of the mannans, led to results that agreed with those of methylation analysis.
NCBI PubMed ID: 3285998Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Czechoslovakia
Methods: 13C NMR, 1H NMR, methylation, MS, acetolysis, precipitation, gas chromatography
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6. Compound ID: 16440
a-D-Manp-(1-2)-+
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a-D-Manp-(1-2)-a-D-Manp-(1-3)-+ |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-2)-a-D-Manp-(1-3)-+ | | |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-3)-+ | | | | |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp |
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Structure type: oligomer
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_241100,IEDB_423157,IEDB_76933,IEDB_857732,IEDB_857734,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72,SB_73,SB_77
The structure is contained in the following publication(s):
- Article ID: 6391
Bovina EV, Deryabin VV "Method for isolation of yeast mannans" -
Moscow Institute of Chemical Technology 135 (1985) 73-77
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7. Compound ID: 16451
a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-D-Man |
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Structure type: oligomer
Trivial name: mannopentaose
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_137485,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_164480,IEDB_76933,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6395
Ogawa K, Matsuda K, Tamari K, Kiyo-oka S "Studies on the glucomannan from Candida utilis. Part III. Immunochemical analysis of the glucomannan from Candida utilis" -
Agricultural and Biological Chemistry 54 (1990) 593-597
A glucomannan isolated from a Candida utilis mutant having a new chemotype was further studied by inhibition of the homologous precipitin reaction with oligosaccharides obtained from the glucomannan by partial acid hydrolysis and controlled acetolysis. Oligosaccharides having at least two consecutive α-(1----2)-linked mannose residues at the non-reducing end and gluco-manno-pentasaccharide were effective inhibitors. Thus, it appears that the glucomannan had two groups of antigenic determinants, one corresponding to the side chains of two, three, and four mannose units connected by α-(1----2)-linkage, and the other corresponding to a side chain composed of an O-α-D-glucopyranosyl-(1----6)-O-α-D-mannopyranosyl- (1----2)-O-α-D-mannopyranosyl-(1----2)-D-mannose unit. These results support a probable structure of repeating units for the glucomannan presented previously. The relative susceptibility of intersaccharidic linkages to acid hydrolysis in the mannan is discussed.
NCBI PubMed ID: 1368530Journal NLM ID: 0370452Publisher: Tokyo: Agricultural Chemical Society Of Japan
Institutions: Department of Fundamental Science, College of Science and Engineering, Iwaki Meisei University, Fukushima, Japan
Methods: acid hydrolysis, precipitin reaction
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8. Compound ID: 16652
/Variants 1/-a-D-Manp-(1-2)-+ /Variants 0/-+
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Subst-(1-2)-EtN-(1--P--6)--a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-myoIno
/Variants 0/ is:
2HOCrt-(1-3)-+
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2HOCrt-(1-2)-Gro-(1--P--1)--
OR (exclusively)
Crt-(1-2)-phSphC18-(1--P--1)--
/Variants 1/ is:
5%a-D-Manp-(1-3)-
OR (exclusively)
15%a-D-Manp-(1-2)-
Subst = protein |
Show graphically |
Structure type: oligomer
Compound class: GPI-anchor
Contained glycoepitopes: IEDB_120354,IEDB_123890,IEDB_130695,IEDB_130701,IEDB_135392,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141807,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_144993,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_474450,IEDB_76933,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6450
Fankhauser C, Homans SW, Thomas-Oates JE, McConville MJ, Desponds C, Conzelmann A, Ferguson MAJ "Structures of glycosylphosphatidylinositol membrane anchors from Saccharomyces cerevisiae" -
Journal of Biological Chemistry 268 (1993) 26365-26374
Metabolic labeling studies suggest that Saccharomyces cerevisiae contains many glycoproteins that are anchored in the lipid bilayer by glycosylphosphatidylinositol membrane anchors. Membrane anchors were purified from a crude yeast membrane protein fraction and analyzed by two-dimensional 1H-1H NMR, fast atom bombardment-mass spectrometry, compositional and methylation linkage analyses, as well as chemical and enzymatic modifications. The yeast glycosylphosphatidylinositol anchors consist of the following structures: ethanolamine-PO4-6(R-2)Man(α1-2)Man(α1-6)Man(α1-4)Glc-NH2(α1-6)myo-inositol-1-PO4-lipid, where R is mainly Man(α1- (80%) with some Man(α1-2)Man(α1- (15%) and Man(α1-3)Man(α1- (5%). The core region of the yeast anchors (ethanolamine-PO4-6Man α 1-2Man α 1-6Man α 1-4GlcNH2 α 1-6myo-inositol-1-PO4) is identical to the conserved core region found in glycosylphosphatidylinositol anchors from protozoa and mammals. The lipid moieties of the total yeast glycosylphosphatidylinositol anchors are mainly ceramides, consisting mostly of C18:0 phytosphingosine and C26:0 fatty acid. However, the lipid moiety of the glycosylphosphatidylinositol anchor of the purified ggp125 protein is a lyso- or diacylglycerol, containing C26:0 fatty acids. This suggests that yeast adds different lipid components to the glycosylphosphatidylinositol anchors of different proteins.
NCBI PubMed ID: 8253761Journal NLM ID: 2985121RPublisher: Baltimore, MD: American Society for Biochemistry and Molecular Biology
Institutions: Institute of Biochemistry, University of Lausanne, Epalinges, Switzerland
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9. Compound ID: 16749
Subst-(1-2)-EtN-(1--P--6)--+
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?%a-D-Manp-(1-3)-+ | Crt-(1-2)-+
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?%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-INO-(1--P--1)--phSphC18
Subst = protein |
Show graphically |
Structure type: oligomer
Compound class: GPI-anchor
Contained glycoepitopes: IEDB_120354,IEDB_123890,IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141807,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_474450,IEDB_76933,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 1735
McConville MJ, Ferguson MAJ "The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes" -
Biochemical Journal 294 (1993) 305-324
No abstract available
NCBI PubMed ID: 8373346Publication DOI: 10.1042/bj2940305Journal NLM ID: 2984726RPublisher: London, UK : Published by Portland Press on behalf of the Biochemical Society
Institutions: Department of Biochemistry, University of Dundee, U.K., Department of Biochemistry, University of Dundee, U.K
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10. Compound ID: 16755
a-D-Manp-(1-2)-a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | | |
| | | | |
a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | | | |
| | | | | |
a-D-Manp-(1-2)-+ | | | | | |
| | | | | | |
-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1- |
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Structure type: polymer biological repeating unit
Compound class: N-glycan, O-linked glycoprotein
Contained glycoepitopes: IEDB_130701,IEDB_134620,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6529
Kobayashi H, Kojimahara T, Takahashi K, Takikawa M, Takahashi SI, Shibata N, Okawa Y, Suzuki S "Structural determination of D-mannans of pathogenic yeasts Candida stellatoidea Type I strains: TIMM 0310 and ATCC 11006 compared to IFO 1397" -
Carbohydrate Research 214 (1991) 131-145
The structures of the cell-wall D-mannans of pathogenic yeasts of Candida stellatoidea Type I strains, IFO 1397, TIMM 0310, and ATCC 11006, were investigated by mild acid and, alkaline hydrolysis, by digestion with the Arthrobacter GJM-1 strain exo-α-D-mannosidase, and by acetolysis. The modified D-mannans and their degradation products were studied by 1H- and 13C-n.m.r. analyses. D-Manno-oligosaccharides released by acid treatment from the parent D-mannans were identified as the homologous β-(1----2)-linked D-manno-oligosaccharides from biose to hexaose, whereas those obtained by alkaline degradation were the homologous α-(1----2)-linked D-mannobiose and D-mannotriose. The acid- and alkali-modified D-mannans lacking 1H-n.m.r. signals above 4.900 p.p.m. [corresponding to β-(1----2)-linked D-mannopyranose units] were acetolyzed with 10:10:1 (v/v) Ac2O-AcOH-H2SO4, and the resultant D-manno-oligosaccharides were also analyzed. It was found that the longest branches of these D-mannans, corresponding to hexaosyl residues, had the following structures: α-D-manp-(1----3)-α-D-manp-(1----2)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man and α-D-manp-(1----2)-α-D-manp-(1----3)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man. These results indicate that the D-mannans of C. stellatoidea Type I strains possess structures in common with the D-mannans of Candida albicans serotype B strain (see ref. 4) containing phosphate-bound β-(1----2)-linked oligo-D-mannosyl residues.
NCBI PubMed ID: 1954627Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan, Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan.
Methods: gel filtration, 13C NMR, 1H NMR, enzymatic digestion, acetolysis, slide-agglutination reaction, acid and alkaline hydrolysis
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11. Compound ID: 16758
a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-2)-+ | | |
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-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1- |
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Structure type: polymer biological repeating unit
Compound class: N-glycan
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6529
Kobayashi H, Kojimahara T, Takahashi K, Takikawa M, Takahashi SI, Shibata N, Okawa Y, Suzuki S "Structural determination of D-mannans of pathogenic yeasts Candida stellatoidea Type I strains: TIMM 0310 and ATCC 11006 compared to IFO 1397" -
Carbohydrate Research 214 (1991) 131-145
The structures of the cell-wall D-mannans of pathogenic yeasts of Candida stellatoidea Type I strains, IFO 1397, TIMM 0310, and ATCC 11006, were investigated by mild acid and, alkaline hydrolysis, by digestion with the Arthrobacter GJM-1 strain exo-α-D-mannosidase, and by acetolysis. The modified D-mannans and their degradation products were studied by 1H- and 13C-n.m.r. analyses. D-Manno-oligosaccharides released by acid treatment from the parent D-mannans were identified as the homologous β-(1----2)-linked D-manno-oligosaccharides from biose to hexaose, whereas those obtained by alkaline degradation were the homologous α-(1----2)-linked D-mannobiose and D-mannotriose. The acid- and alkali-modified D-mannans lacking 1H-n.m.r. signals above 4.900 p.p.m. [corresponding to β-(1----2)-linked D-mannopyranose units] were acetolyzed with 10:10:1 (v/v) Ac2O-AcOH-H2SO4, and the resultant D-manno-oligosaccharides were also analyzed. It was found that the longest branches of these D-mannans, corresponding to hexaosyl residues, had the following structures: α-D-manp-(1----3)-α-D-manp-(1----2)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man and α-D-manp-(1----2)-α-D-manp-(1----3)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man. These results indicate that the D-mannans of C. stellatoidea Type I strains possess structures in common with the D-mannans of Candida albicans serotype B strain (see ref. 4) containing phosphate-bound β-(1----2)-linked oligo-D-mannosyl residues.
NCBI PubMed ID: 1954627Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan, Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan.
Methods: gel filtration, 13C NMR, 1H NMR, enzymatic digestion, acetolysis, slide-agglutination reaction, acid and alkaline hydrolysis
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12. Compound ID: 16759
a-D-Manp-(1-2)-a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-2)-a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | | | |
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a-D-Manp-(1-2)-+ | | | | | |
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-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1- |
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Structure type: polymer biological repeating unit
Compound class: N-glycan, O-linked glycoprotein
Contained glycoepitopes: IEDB_130701,IEDB_134620,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6529
Kobayashi H, Kojimahara T, Takahashi K, Takikawa M, Takahashi SI, Shibata N, Okawa Y, Suzuki S "Structural determination of D-mannans of pathogenic yeasts Candida stellatoidea Type I strains: TIMM 0310 and ATCC 11006 compared to IFO 1397" -
Carbohydrate Research 214 (1991) 131-145
The structures of the cell-wall D-mannans of pathogenic yeasts of Candida stellatoidea Type I strains, IFO 1397, TIMM 0310, and ATCC 11006, were investigated by mild acid and, alkaline hydrolysis, by digestion with the Arthrobacter GJM-1 strain exo-α-D-mannosidase, and by acetolysis. The modified D-mannans and their degradation products were studied by 1H- and 13C-n.m.r. analyses. D-Manno-oligosaccharides released by acid treatment from the parent D-mannans were identified as the homologous β-(1----2)-linked D-manno-oligosaccharides from biose to hexaose, whereas those obtained by alkaline degradation were the homologous α-(1----2)-linked D-mannobiose and D-mannotriose. The acid- and alkali-modified D-mannans lacking 1H-n.m.r. signals above 4.900 p.p.m. [corresponding to β-(1----2)-linked D-mannopyranose units] were acetolyzed with 10:10:1 (v/v) Ac2O-AcOH-H2SO4, and the resultant D-manno-oligosaccharides were also analyzed. It was found that the longest branches of these D-mannans, corresponding to hexaosyl residues, had the following structures: α-D-manp-(1----3)-α-D-manp-(1----2)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man and α-D-manp-(1----2)-α-D-manp-(1----3)-α-D-manp+ ++-(1----2)-α-D-manp- (1----2)-α-D-manp-(1----2)-D-Man. These results indicate that the D-mannans of C. stellatoidea Type I strains possess structures in common with the D-mannans of Candida albicans serotype B strain (see ref. 4) containing phosphate-bound β-(1----2)-linked oligo-D-mannosyl residues.
NCBI PubMed ID: 1954627Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan, Second Department of Hygienic Chemistry, Tohoku College of Pharmacy, Miyagi, Japan.
Methods: gel filtration, 13C NMR, 1H NMR, enzymatic digestion, acetolysis, slide-agglutination reaction, acid and alkaline hydrolysis
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13. Compound ID: 16769
a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | |
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a-D-Manp-(1-2)-+ | | | |
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-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1- |
Show graphically |
Structure type: polymer chemical repeating unit
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_164480,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6541
Kobayashi H, Shibata N, Yonezu T, Suzuki S "Application of mild acetolysis to confirm the comb-like structure of cell wall mannan from Pichia pastoris IFO 0948 strain" -
Chemical and Pharmaceutical Bulletin 36 (1988) 3168-3172
Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
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14. Compound ID: 16798
a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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b-D-Manp-(1-2)-b-D-Manp-(1-2)-a-D-Manp-(1--P--?)--a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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-6)-a-D-Manp-(1- |
Show graphically |
Structure type: polymer chemical repeating unit
Trivial name: mannan
Contained glycoepitopes: IEDB_130701,IEDB_133966,IEDB_136104,IEDB_137485,IEDB_140116,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_141834,IEDB_143632,IEDB_144983,IEDB_144995,IEDB_144996,IEDB_152206,IEDB_153220,IEDB_153762,IEDB_153763,IEDB_1539315,IEDB_164479,IEDB_164480,IEDB_474450,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
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15. Compound ID: 16814
a-D-Manp-(1-3)-+
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a-D-Glcp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+
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a-D-Glcp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ |
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a-D-Manp-(1-3)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | |
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a-D-Manp-(1-2)-a-D-Manp-(1-2)-+ | | |
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a-D-Manp-(1-2)-+ | | | |
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-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1-6)-a-D-Manp-(1- |
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Structure type: polymer chemical repeating unit
Trivial name: glucomannan
Contained glycoepitopes: IEDB_130701,IEDB_136104,IEDB_140116,IEDB_141111,IEDB_141793,IEDB_141795,IEDB_141828,IEDB_141829,IEDB_141830,IEDB_141831,IEDB_141832,IEDB_141833,IEDB_142488,IEDB_143632,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_152206,IEDB_153220,IEDB_153756,IEDB_153762,IEDB_153763,IEDB_164174,IEDB_164175,IEDB_164176,IEDB_164480,IEDB_174840,IEDB_76933,IEDB_857732,IEDB_857735,IEDB_983930,IEDB_983931,SB_136,SB_191,SB_192,SB_196,SB_197,SB_198,SB_44,SB_67,SB_72
The structure is contained in the following publication(s):
- Article ID: 6586
Kogan G, Sandula J, Simkovicova V "Glucomannan from Candida utilis. Structural investigation" -
Folia Microbiologica 38 (1993) 219-224
Structure of the glucomannan isolated from the cell walls of Candida utilis has been investigated using acetolysis fragmentation, methylation analysis and NMR spectroscopy. The structure of the glucomannan resembles that of the cellular mannans of other Candida species, except that the longer tetra- and pentassacharide side-chains are terminated with a glucosyl residue. Presence of the nonreducing glucosyl groups at the ends of the side-chains caused the C. utilis not to cross-react in a double immunodiffusion test with other Candida species that possess mannan antigens and cross-react with Hansenula species with glucomannan antigens.
NCBI PubMed ID: 8365697Journal NLM ID: 0376757Publisher: New York: Springer
Institutions: Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia
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